Given how BrilliantImagery and some similar software have traditionally worked, every time exposure was ramped and/or a sequence was stabilized, the selected portion of every image in the sequence had to be rendered and this rendering process was where the majority of the processing time has been spent. The result was that even a small change to a single exposure, or a minor tweak to a crop made for a time consuming process. BrilliantImagery has since been changed so that the relevant, underlying, and processed raw data is saved so that, as long as you don't want to change the referenced area of each image, additional runs take minimal time.
This was tested on 64 bit Windows 10, build 18362. Hopefully it'll work on other builds and versions but due to a lack of availability, that's yet to be known. Hopefully, in time, we'll be testing against more versions of Windows. If it doesn't work for you, we'd love to know!
BrillinatImagery is a package and app for working with DNG images and image sequences. It can do things such as: